Niecy Nash as Desna Simms
The owner of the salon, a gangster stuck in a moll's body, a discerning curator of the female oddities who make up her crew. Desna will throw down and fight to the death but also eats Lean Cuisines and worries about getting fat.
Carrie Preston as Polly
A mild-mannered preppy who works as a manicurist at the nail salon. Polly has recently been released from prison, where she did time for identity theft on seniors. Beneath that southern gentility beats the heart of a con artist and master manipulator.
Karrueche Tran as Virginia
Our troubled ingénue, in a strippery kind of way. What you see first in Virginia - the bored hotness, the attitude, the bluster - disguises her truth, which is that she’s desperately looking for a place to belong.
Jenn Lyon as Jennifer
Desna's best friend and co-worker, a hard woman with a filthy sense of humor, used to be wild but has settled down a lot. Tenuously sober, loves her kids more than anything but sometimes feels trapped.
Judy Reyes as Quiet Ann
A woman of few words, an enigma who discovered women in prison and discovered is an understatement - mastered is more like it. Now her thing is macking bored Florida housewives and being Desna’s driver and muscle when necessary.
Dean Norris as Uncle Daddy
A larger than life, dangerous, deeply Catholic bisexual who runs go-go joints up and down the Gulf Coast. He raised Roller and Bryce when their father was shot. This is a man who lives his numerous contradictions right out in the open.
Harold Perrineau as Dean
Desna’s autistic brother, a male Blanche Dubios, a hothouse flower and budding outsider artist who lives in a hermetically sealed world maintained by his loving, overprotective sister.
Jason Antoon as Dr. Ken Brickman
A bona fide doctor with a decidedly un-bona fide job, working at Uncle Daddy’s illicit drug clinic.
Suleka Mathew as Arlene Branch
Suleka Mathew will play Arlene Branch, a tough sexy cop who enters into a risky relationship with Quiet Ann.
Evan Daigle as Toby
Toby is Uncle Daddy’s right-hand man and favorite boy toy.